<p>After taking the opener of this three-game series Tuesday night, the Padres go for the series victory Wednesday night in Philadelphia. Lefty Blake Snell makes his first start of this season for San Diego here against Zack Wheeler for the Phillies.</p>
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<h2>MLB Betting Odds</h2>
<p>Wednesday's baseball betting lines opened Philly and Wheeler at around -140 over San Diego and Snell, with an over/under of 7.5 runs. Early betting action then bumped the Phillies a dime to -150.</p>
<h2>Padres-Phillies MLB Betting Preview </h2>
<p>San Diego grabbed the opener of this series Tuesday night, 3-0. The Padres scored one run in the fifth inning and two in the seventh while getting five shutout innings from starter Mike Clevinger and four shutout innings from their bullpen.</p>
<p>San Diego won Tuesday as a +100 “underdog” on the dime line, and the game played under a total of eight runs.</p>
<p>With Tuesday's win, the Padres are 3-1 over their last four games. At 23-13 overall, San Diego trails the first-place Dodgers by one game in the NL West.</p>
<p>With Tuesday's loss, Philadelphia is 4-2 over its last six games. At 17-19 overall, the Phillies are tied for second place in the NL East with Miami, six games behind the first-place Mets.</p>
<p>This series is the first meeting between these teams this season. Last year Philly took the season series from the Padres four games to two.</p>
<h2>Wednesday's Pitching Match-Up</h2>
<p><a class="advblue" href="https://www.sportsbettingstats.com/mlb/pitcherlog/48283&quot; title="Zack Wheeler Pitching Stats">Wheeler</a> is 2/6 on quality starts this season and two for his last three. Last Thursday, he gave up three runs and six hits through 5 1/3 innings of a 9-7 Philadelphia victory over the Dodgers. But over his two starts previous to that, he allowed zero runs and seven hits through 13 2/3 innings, with five walks and 14 strikeouts.</p>
<p>This season, the Phillies are 2-4 with Wheeler, which actually sounds about right.</p>
<p>In his only start last year against San Diego, Wheeler tossed seven innings of four-hit, shutout ball in a 4-3 Philly win.</p>
<p>Lefty <a class="advblue" href="https://www.sportsbettingstats.com/mlb/pitcherlog/79509&quot; title="Blake Snell Pitching Logs">Snell</a> will be making his first start this season after rehabbing from a couple of injuries. Last year the former AL Cy Young Award winner posted a 4.20 ERA and a 1.32 WHIP through 128 2/3 innings of work, with 170 whiffs against 69 walks.</p>
<p>The Padres played 12-15 with Snell last season.</p>
<p>Over two starts last year against Philadelphia, Snell allowed three runs and four hits through nine innings, with six walks and 12 strikeouts. The Padres split those two games.</p>
<h2>Splits With the Sticks</h2>
<p>San Diego is batting .222 against right-handed pitching this season, with a .309 team OBP and a .336 team slugging percentage. The Padres have also scored at least five runs five times over their last six games.</p>
<p>Philadelphia is slashing .258/.316/.454 against left-handed pitching. But left-handed stick Bryce Harper has missed the last two games with a sore elbow and is questionable for Wednesday night.</p>
<h2>The Bullpens</h2>
<p>The San Diego bullpen owns a 4.05 ERA this season, along with a 1.15 WHIP.</p>
<p>The Phillies pen owns a 4.42 ERA and a 1.40 WHIP.<br />
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<span style="font-size:14px; color:#008000;">Get more details:</span> <a class="advblue" href="https://www.sportsbettingstats.com/mlb/matchup/1602056">San Diego at Philadelphia 5/18/22 Betting Stats</a>
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<h2>MLB Betting Trends</h2>
<ul>
<li>The Padres are 13-6 on the road this season and 13-10 against right-handed starters.</li>
<li>Philadelphia is 9-10 at home and 6-4 against left-handed starters.</li>
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<h2>Totals Report</h2>
<ul>
<li>The overs are 18-17 in Padres games this season.</li>
<li>The overs are 18-14 in Phillies games.</li>
<li>The unders are 9-8 at Citizens Bank Park this season.</li>
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