San Diego Padres at San Francisco Giants Odds & Picks

April 11, 9:45 PM EDT

Betting Odds

SD +135/SF -145

The defending NL West champion Giants begin their rivalry series with the Padres Monday night out by McCovey Cove. Lefty Alex Wood hits the hill for the home team here against former Japanese Leaguer Nick Martinez for the visitors.

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MLB Betting Odds

Monday's baseball betting lines opened San Francisco at around -140 over San Diego, with an over/under of eight runs. Early betting action then bumped the Giants a nickel to -145, and that total to 8.5.

Padres-Giants MLB Betting Preview

San Diego just took three out of four games from the Diamondbacks in Phoenix over the weekend, winning Sunday's series finale 10-5. The Padres lost the first game of that series, then won the last three.

San Diego is trying to bounce back this season after going a disappointing 79-83 last season, playing under their wins over/under of 93.5. This season the Padres are playing against a wins O/U of 88.5.

San Francisco, meanwhile, just took two of three games at home from Miami, winning Sunday's series rubber match 3-2. The Giants are trying to pull off a repeat performance of last season when they won an amazing 107 games to win the NL West. They also played over their season, wins O/U of 73.5 by 34 games!

This season San Francisco is playing against a wins over/under of 85.5.

Last year the Giants took the season series from San Diego 11 games to eight.

Monday's Pitching Match-Up

Lefty Wood hit 9/26 on quality starts last season. On the whole, he posted a 3.83 ERA and a 1.18 WHIP, which is nice, through 138 2/3 innings, with 152 strikeouts against 39 walks.

San Francisco played a very nice 19-7 with Wood last season.

Somehow, Wood missed San Diego last year. Martinez, meanwhile, is back in the Majors after playing in Japan the last four years. He posted a 17-30 record and a 4.77 ERA with Texas from 2014-17, then went 23-23 with an ERA under three in four seasons in the Japan League. This will be Martinez' first-ever start against San Francisco.

Splits With the Sticks

San Diego batted .241 against left-handed pitching last season, with a .324 team OBP and a .380 team slugging percentage. But the Padres are playing without one big stick right now with SS Fernando Tatis out after wrist surgery. San Francisco slashed .250/.328/.447 against right-handed pitching last season.

The Bullpens

The Padres bullpen posted a 3.62 ERA last season, along with a 1.24 WHIP. The Giants pen put up a 2.99 ERA last season and a 1.13 WHIP, both of which led the Majors.

MLB Betting Trends

  • The Padres played 34-47 on the road last season.
  • The Giants played 54-27 at home last season.
  • The Padres played 24-20 against left-handed starters last season.
  • The Giants played an ML-best 79-35 against right-handed starters last season.

Totals Report

  • The Under is 3-1 in Padres games this season.
  • The Under is 2-1 in Giants games this season.
  • The totals played 40-40 at Oracle Park last season.
  • Overs played 12-7 in Padres-Giants games last season.

Padres at Giants Prediction 4/11/22

We gotta give Wood the edge in the pitching match-up, and we give San Francisco edges with the sticks and in the bullpen comparison. So we're playing the Giants tonight, giving the -145 on the dime line.     

Free Pick: 
Take San Francisco -145