San Diego Padres at San Francisco Giants Odds & Free Picks

September 15, 9:45 PM EDT

Betting Odds

SD -110/SF -110
8.5un -113

After taking the first two games of this series, the streaking Giants shoot for more against the fading Padres Wednesday night in San Francisco. Opener Dominic Leone hits the hill for the Giants for the second time in this series against Joe Musgrove for San Diego. How are we playing this game with our free baseball betting pick?

MLB Betting Odds

Wednesday's baseball betting lineslist San Diego and San Francisco at pick'em', with an over/under of 8.5 runs. Both figures were holding steady in the early betting action.

The Padres could also be found getting around +145, giving the run and a half on the run line.

Padres-Giants MLB Betting Preview

San Francisco took the opener of this series Monday night 9-1, then won Tuesday's game 6-1. The Giants won as +100 home dogs Monday against Yu Darvish, then as -190 favorites Tuesday. With Tuesday's win, San Francisco now owns a nine-game winning streak, scoring a ton of runs along the way. And yet, even at 94-50 overall, the best record in baseball, the Giants only lead the NL West by 2.5 games over the second-place Dodgers. So San Francisco just has to keep winning. With Tuesday's loss, San Diego now owns a five-game losing skid, scoring a total of six runs over that span. At 74-70 overall, the Padres are now one game behind St. Louis in the battle for the second National League wild-card spot. San Francisco leads the season series with San Diego seven games to four.

Wednesday's Pitching Match-Up

Leone is making his fourth start of this season in an opener role, to go along with 43 appearances in relief. Most recently, Monday night, he tossed two innings of shutout ball against these Padres, and over his last six appearances, he's allowed two runs - zero earned - and two hits through 7 2/3 innings. San Francisco is 3-0 when Leone starts this season. Leone will probably go an inning or two Wednesday, like he did Monday, then turn the game over to the Giants' very capable bullpen. By our strict standards, Musgrove is 12/27 on quality starts this year and two for his last three. Eleven days ago, he allowed two runs and seven hits through 5 1/3 innings of a 10-2 Padres win over Houston. And over his last three starts, he's allowed just three runs and 13 hits through 20 1/3 innings, with five walks against 22 strikeouts. San Diego is 15-12 with Musgrove this year, 3-0 over his last three starts. However, over two starts already this season against San Francisco, Musgrove got clipped for nine ER and 12 hits, including three home runs, through 10 innings. The Padres lost both those games.

Splits With the Sticks

San Diego is batting .240 against right-handed pitching this season, with a .319 team OBP and a .405 team slugging percentage. San Francisco is slashing .247/.326/.448 against right-handed pitching.

The Bullpens

The Padres bullpen owns a 3.34 ERA, along with a 1.22 WHIP and a 2.76 K/BB ratio. The Giants pen owns a 3.01 ERA, which ranks No. 1 in the Majors, a 1.08 WHIP, which also ranks No. 1, and a 3.07 K/BB ratio, which ranks No. 2.

MLB Betting Trends

  • The Padres are 30-38 on the road this season.
  • The Giants are 46-23 at home.
  • The Padres are 50-53 against right-handed starters this season.
  • The Giants are 68-31 against right-handed starters.

Totals Report

Overs are 74-66 in Padres games this season. Unders are 74-65 in Giants games. Overs are 6-5 in Padres-Giants games this season.

Padres at Giants Prediction 9/15/21

Musgrove's been very good as of late, but we're calling the pitching match-up a push because the San Francisco pen, which should get plenty of action here, is just super. From there, we give the Giants the edge in the splits with the sticks, and San Francisco is just hot, while San Diego is not. And momentum means a ton to us when handicapping baseball games. So we like the Giants at pick'em for our free baseball betting pick for Wednesday.  

Free Pick: 
Take San Francisco -110